Anti-PDGFRB Monoclonal Antibody (10H8)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC756	Anti-PDGFRB Antibody (10H8)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC756-P	Anti-PDGFRB Antibody (10H8), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC756-A	Anti-PDGFRB Antibody (10H8), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC756-H	Anti-PDGFRB Antibody (10H8), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC756-B	Anti-PDGFRB Antibody (10H8), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC756

Anti-PDGFRB Antibody (10H8)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC756-P

Anti-PDGFRB Antibody (10H8), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC756-A

Anti-PDGFRB Antibody (10H8), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC756-H

Anti-PDGFRB Antibody (10H8), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC756-B

Anti-PDGFRB Antibody (10H8), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-PDGFRB Monoclonal Antibody (10H8)
- Product Description:
  
  The Anti-PDGFRB antibody is a human monoclonal antibody recommended for use in ELISA, neutralization and other applications. This antibody is specific to PDGFRB and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Neutralization
  
  Target:
  
  PDGFRB
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human PDGFRB.
  
  Immunogen:
  
  Recombinant Human PDGFRB protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  10H8
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-PDGFRB Monoclonal Antibody (10H8) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

PDGFRB

Protein Name

Platelet-derived growth factor receptor beta

Introduction

The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton.

Alternative Names

IMF1; KOGS; IBGC4; JTK12; OPDKD; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1

Gene ID

5159

UniProt

P09619

Molecule Mass

CD Molecules, Cytokine/Chemokine Receptors

Cell Line Specificity

Cancer enhanced

Function

Tyrosine-protein kinase that acts as a cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.

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