Anti-PDGFD Monoclonal Antibody (7G11)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC289	Anti-PDGFD Antibody (7G11)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC289-P	Anti-PDGFD Antibody (7G11), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC289-A	Anti-PDGFD Antibody (7G11), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC289-H	Anti-PDGFD Antibody (7G11), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC289-B	Anti-PDGFD Antibody (7G11), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC289

Anti-PDGFD Antibody (7G11)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC289-P

Anti-PDGFD Antibody (7G11), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC289-A

Anti-PDGFD Antibody (7G11), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC289-H

Anti-PDGFD Antibody (7G11), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC289-B

Anti-PDGFD Antibody (7G11), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-PDGFD Monoclonal Antibody (7G11)
- Product Description:
  
  The Anti-PDGFD antibody is a human monoclonal antibody recommended for use in ELISA, functional assay, immunohistochemistry and other applications. This antibody specifically targets PDGFD and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Functional Assay, Immunohistochemistry
  
  Target:
  
  PDGFD
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human PDGFD.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  7G11
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-PDGFD Monoclonal Antibody (7G11) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

PDGFD

Protein Name

Platelet-derived growth factor D

Introduction

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.

Alternative Names

PDGFD; platelet derived growth factor D; IEGF; SCDGFB; MSTP036; SCDGF-B; PDGF-DD; Platelet derived growth factor-DD

Gene ID

80310

UniProt

Q9GZP0

Subcellular Location

Secreted

Cell Line Specificity

Low cancer specificity

Function

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).

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