Anti-PDE4D Monoclonal Antibody (B-9E4)

Anti-PDE4D Monoclonal Antibody (B-9E4)

Cat No: ASZ1C1468

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
Clone ID:
B-9E4
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASZ1C1468 Anti-PDE4D Antibody (B-9E4) Mouse IgG None $460
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  • Anti-PDE4D Monoclonal Antibody (B-9E4)
    • Product Description:
      The Anti-PDE4D antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human PDE4D.
      Applications:
      Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
      Source:
      Mouse
      Target:
      PDE4D
      Target Species:
      Human
      Specificity:
      This antibody reacts with human Phosphodiesterase 4D (PDE4D).
      Clonality:
      Monoclonal
      Clone ID:
      B-9E4
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      0.02% sodium azide
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-PDE4D Monoclonal Antibody (B-9E4) Applications
    • Recommended Dilution:
      Western Blot: 1:500-1:5000
      Immunohistochemistry: 1:50-1:200
      Immunocytochemistry: 1:50-1:200
      Note:
      Optimal dilutions/concentrations should be determined by the end user.
Protein Name
3',5'-cyclic-AMP phosphodiesterase 4D
Introduction
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
Alternative Names
ACRDYS2; DPDE3; HSPDE4D; PDE43N2; STRK1; PDE4D
Gene ID
UniProt
Subcellular Location
Apical cell membrane
Tissue Specificity
Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle.
Cell Line Specificity
Low cancer specificity
Function
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
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