Anti-PCDHB15 Monoclonal Antibody (B-15E5)

Anti-PCDHB15 Monoclonal Antibody (B-15E5)

Cat No: ASZ1C1450

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
Clone ID:
B-15E5
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASZ1C1450 Anti-PCDHB15 Antibody (B-15E5) Mouse IgG None $460
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  • Anti-PCDHB15 Monoclonal Antibody (B-15E5)
    • Product Description:
      The Anti-PCDHB15 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human PCDHB15.
      Applications:
      Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
      Source:
      Mouse
      Target:
      PCDHB15
      Target Species:
      Human
      Specificity:
      This antibody reacts with human Protocadherin Beta 15 (PCDHB15).
      Clonality:
      Monoclonal
      Clone ID:
      B-15E5
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      0.02% sodium azide
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-PCDHB15 Monoclonal Antibody (B-15E5) Applications
    • Recommended Dilution:
      Western Blot: 1:500-1:5000
      Immunohistochemistry: 1:50-1:200
      Immunocytochemistry: 1:50-1:200
      Note:
      Optimal dilutions/concentrations should be determined by the end user.
Protein Name
Protocadherin beta-15
Introduction
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Alternative Names
PCDH-BETA15
Gene ID
UniProt
Subcellular Location
Cell membrane
Cell Line Specificity
Cancer enhanced
Function
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
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