Anti-PADI3 Monoclonal Antibody (B-1B2)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1435	Anti-PADI3 Antibody (B-1B2)	Mouse IgG2b, Kappa		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1435

Anti-PADI3 Antibody (B-1B2)

Mouse IgG2b, Kappa

None

$460

Add

Anti-PADI3 Monoclonal Antibody (B-1B2)
- Product Description:
  
  The Anti-PADI3 antibody is a mouse monoclonal antibody recommended for western blot and other applications. This antibody specifically targets human and rat PADI3.
  
  Applications:
  
  Western Blot
  
  Source:
  
  Mouse
  
  Target:
  
  PADI3
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Peptidyl Arginine Deiminase 3 (PADI3).
  
  Immunogen:
  
  Recombinant PADI3 protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  B-1B2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.05% Proclin 300
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-PADI3 Monoclonal Antibody (B-1B2) Applications
- Recommended Dilution:
  
  Western Blot: 0.01-3 µg/mL
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Protein-arginine deiminase type-3

Introduction

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes.

Alternative Names

PAD3; PDI3

Gene ID

51702

UniProt

Q9ULW8

Related Disease

Uncombable hair syndrome 1 (UHS1)

Subcellular Location

Cytoplasm

Tissue Specificity

Hair follicles, and epidermis at very low levels.

Cell Line Specificity

Cancer enhanced

Function

Catalyzes the deimination of arginine residues of proteins.

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