-
Anti-OAZ1 Monoclonal Antibody (F-14E10)
-
Product Description:The Anti-OAZ1 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human OAZ1.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:OAZ1Target Species:HumanSpecificity:This antibody reacts with human Ornithine Decarboxylase Antizyme 1 (OAZ1).Clonality:MonoclonalClone ID:F-14E10Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
-
-
Anti-OAZ1 Monoclonal Antibody (F-14E10) Applications
-
Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
-
Protein Name
Ornithine decarboxylase antizyme 1
Introduction
The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene.
Alternative Names
AZI; OAZ
Gene ID
UniProt
Cell Line Specificity
Low cancer specificity
Customer Reviews
There are no reviews for Product Name.
Submit a review and receive an Amazon gift card.
Publications
There are no publications for Product Name.
If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward
