Anti-NPY5R Monoclonal Antibody (A-13B1)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1377	Anti-NPY5R Antibody (A-13B1)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1377

Anti-NPY5R Antibody (A-13B1)

Mouse IgG

None

$460

Add

Anti-NPY5R Monoclonal Antibody (A-13B1)
- Product Description:
  
  The Anti-NPY5R antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human NPY5R.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  NPY5R
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Neuropeptide Y Receptor Y5 (NPY5R).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  A-13B1
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-NPY5R Monoclonal Antibody (A-13B1) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Neuropeptide Y receptor type 5

Introduction

The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene.

Alternative Names

NPY5-R; NPYR5; NPYY5-R

Gene ID

4889

UniProt

Q15761

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Tissue Specificity

Brain; hypothalamus.

Cell Line Specificity

Cancer enriched

Function

Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

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