Anti-NECTIN4 Monoclonal Antibody (15C10)

Anti-NECTIN4 Monoclonal Antibody (15C10)

Cat No: ASPC867

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Enzyme-Linked Immunosorbent Assay, Western Blot
Clone ID:
15C10
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC867 Anti-NECTIN4 Antibody (15C10) Mouse IgG None $460 4-6 weeks
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ASPC867-1 Anti-NECTIN4 Antibody (15C10), scFv fragment Mouse scFv His tag None $460 In stock
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ASPC867-P Anti-NECTIN4 Antibody (15C10), PE Mouse IgG PE $1,180 4-6 weeks
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ASPC867-A Anti-NECTIN4 Antibody (15C10), APC Mouse IgG APC $980 4-6 weeks
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ASPC867-H Anti-NECTIN4 Antibody (15C10), HRP Mouse IgG HRP $600 4-6 weeks
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ASPC867-B Anti-NECTIN4 Antibody (15C10), Biotin Mouse IgG Biotin $680 4-6 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-NECTIN4 Monoclonal Antibody (15C10)
    • Product Description:
      The Anti-NECTIN4 antibody is a mouse monoclonal antibody recommended for use in ELISA, western blot and other applications. This antibody specifically targets NECTIN4 and demonstrates reactivity with human.
      Applications:
      Enzyme-Linked Immunosorbent Assay, Western Blot
      Target:
      NECTIN4
      Target Species:
      Human
      Specificity:
      This antibody reacts with human NECTIN4.
      Clonality:
      Monoclonal
      Clone ID:
      15C10
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-NECTIN4 Monoclonal Antibody (15C10) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
NECTIN4
Protein Name
Nectin-4
Introduction
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.
Alternative Names
Nectin Cell Adhesion Molecule 4; Nectin-4; PVRL4
Gene ID
UniProt
Related Disease
Ectodermal dysplasia-syndactyly syndrome 1 (EDSS1)
Subcellular Location
Cell membrane
Tissue Specificity
Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma.
Cell Line Specificity
Cancer enhanced
Function
Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. (Microbial infection) Acts as a receptor for measles virus.
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