Anti-NDUFS1 Monoclonal Antibody (D-1H2)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1318	Anti-NDUFS1 Antibody (D-1H2)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1318

Anti-NDUFS1 Antibody (D-1H2)

Mouse IgG

None

$460

Add

Anti-NDUFS1 Monoclonal Antibody (D-1H2)
- Product Description:
  
  The Anti-NDUFS1 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human NDUFS1.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  NDUFS1
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human NADH:Ubiquinone Oxidoreductase Core Subunit S1 (NDUFS1).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  D-1H2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-NDUFS1 Monoclonal Antibody (D-1H2) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

Introduction

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

Alternative Names

CI-75Kd; CI-75k; PRO1304

Gene ID

4719

UniProt

P28331

Related Disease

Mitochondrial complex I deficiency, nuclear type 5 (MC1DN5)

Subcellular Location

Mitochondrion inner membrane

Cell Line Specificity

Low cancer specificity