Anti-MUC17 Monoclonal Antibody - Amerigo Scientific

Subcat	Description	Isotype	Conjugate	Price
ASPC1280	Anti-MUC17 Antibody	Mouse IgG1, Kappa	None	$460	Add
ASPC1280-A	Anti-MUC17 Antibody, APC	Mouse IgG1, Kappa	APC	$980	Add
ASPC1280-B	Anti-MUC17 Antibody, Biotin	Mouse IgG1, Kappa	Biotin	$680	Add
ASPC1280-H	Anti-MUC17 Antibody, HRP	Mouse IgG1, Kappa	HRP	$600	Add
ASPC1280-P	Anti-MUC17 Antibody, PE	Mouse IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1280

Anti-MUC17 Antibody

Mouse IgG1, Kappa

None

$460

Add

ASPC1280-A

Anti-MUC17 Antibody, APC

Mouse IgG1, Kappa

APC

$980

Add

ASPC1280-B

Anti-MUC17 Antibody, Biotin

Mouse IgG1, Kappa

Biotin

$680

Add

ASPC1280-H

Anti-MUC17 Antibody, HRP

Mouse IgG1, Kappa

HRP

$600

Add

ASPC1280-P

Anti-MUC17 Antibody, PE

Mouse IgG1, Kappa

$1,180

Add

Anti-MUC17 Monoclonal Antibody
- Product Description:
  
  The Anti-MUC17 antibody is a mouse monoclonal antibody recommended for use in flow cytometry, enzyme-linked immunosorbent assay and other applications. This antibody specifically targets MUC17 and demonstrates reactivity with human.
  
  Applications:
  
  Flow Cytometry, Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  MUC17
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human MUC17.
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-MUC17 Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

MUC17

Protein Name

Mucin-17

Introduction

The protein encoded by this gene is a membrane-bound mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize on the cell surface, while the C-terminus interacts with the scaffold protein PDZ domain containing 1 (PDZK1).

Alternative Names

MUC-17; MUC-3; MUC3

Gene ID

140453

UniProt

Q685J3

Subcellular Location

Isoform 1: Cell membrane; Single-pass membrane protein. Isoform 2: Secreted

Tissue Specificity

Expressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. Highly expressed in pancreatic adenocarcinoma tissue (at protein level). Expression is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers.

Cell Line Specificity

Group enriched

Function

Probably plays a role in maintaining homeostasis on mucosal surfaces.

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