Anti-MSLN Monoclonal Antibody - Amerigo Scientific

Subcat	Description	Isotype	Conjugate	Price
ASPC1271	Anti-MSLN Antibody	Human IgG1, Kappa	None	$460	Add
ASPC1271-A	Anti-MSLN Antibody, APC	Human IgG1, Kappa	APC	$980	Add
ASPC1271-B	Anti-MSLN Antibody, Biotin	Human IgG1, Kappa	Biotin	$680	Add
ASPC1271-H	Anti-MSLN Antibody, HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC1271-P	Anti-MSLN Antibody, PE	Human IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1271

Anti-MSLN Antibody

Human IgG1, Kappa

None

$460

Add

ASPC1271-A

Anti-MSLN Antibody, APC

Human IgG1, Kappa

APC

$980

Add

ASPC1271-B

Anti-MSLN Antibody, Biotin

Human IgG1, Kappa

Biotin

$680

Add

ASPC1271-H

Anti-MSLN Antibody, HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC1271-P

Anti-MSLN Antibody, PE

Human IgG1, Kappa

$1,180

Add

Anti-MSLN Monoclonal Antibody
- Product Description:
  
  The Anti-MSLN antibody is a human monoclonal antibody recommended for use in flow cytometry, enzyme-linked immunosorbent assay and other applications. This antibody specifically targets MSLN and demonstrates reactivity with human and mouse.
  
  Applications:
  
  Flow Cytometry, Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  MSLN
  
  Specificity:
  
  This antibody reacts with MSLN.
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-MSLN Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

MSLN

Protein Name

Mesothelin

Introduction

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.

Alternative Names

Mesothelin; Pre-Pro-Megakaryocyte-Potentiating Factor; CAK1 Antigen; MPF; Soluble MPF Mesothelin Related Protein; Megakaryocyte Potentiating Factor; SMRP

Gene ID

10232

UniProt

Q13421

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Megakaryocyte-potentiating factor: Secreted. Isoform 3: Secreted.

Tissue Specificity

Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).

Cell Line Specificity

Cancer enhanced

Function

Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.

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