Anti-MICA Monoclonal Antibody (2F4)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC285	Anti-MICA Antibody (2F4)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC285-P	Anti-MICA Antibody (2F4), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC285-A	Anti-MICA Antibody (2F4), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC285-H	Anti-MICA Antibody (2F4), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC285-B	Anti-MICA Antibody (2F4), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC285

Anti-MICA Antibody (2F4)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC285-P

Anti-MICA Antibody (2F4), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC285-A

Anti-MICA Antibody (2F4), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC285-H

Anti-MICA Antibody (2F4), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC285-B

Anti-MICA Antibody (2F4), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-MICA Monoclonal Antibody (2F4)
- Product Description:
  
  The Anti-MICA antibody is a human monoclonal antibody recommended for use in ELISA and other applications. This antibody specifically targets MICA and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  MICA
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human MICA.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  2F4
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-MICA Monoclonal Antibody (2F4) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

MICA

Protein Name

MHC class I polypeptide-related sequence A

Introduction

This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.

Alternative Names

MICA; MHC class I polypeptide-related sequence A; MIC-A; PERB11.1; HLA class I antigen; stress inducible class I homolog; MHC class I chain-related protein A

Gene ID

100507436

UniProt

Q29983

Subcellular Location

Cell membrane

Function

Widely expressed membrane-bound protein which acts as a ligand to stimulate an activating receptor KLRK1/NKG2D, expressed on the surface of essentially all human natural killer (NK), gammadelta T and CD8 alphabeta T-cells.

Customer Reviews

There are no reviews for Product Name.

Submit a review and receive an Amazon gift card.

Publications

There are no publications for Product Name.

If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward