Anti-MGP Monoclonal Antibody (D-2F9)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1215	Anti-MGP Antibody (D-2F9)	Mouse IgG1, Kappa		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1215

Anti-MGP Antibody (D-2F9)

Mouse IgG1, Kappa

None

$460

Add

Anti-MGP Monoclonal Antibody (D-2F9)
- Product Description:
  
  The Anti-MGP antibody is a mouse monoclonal antibody recommended for western blot and other applications. This antibody specifically targets human MGP.
  
  Applications:
  
  Western Blot
  
  Source:
  
  Mouse
  
  Target:
  
  MGP
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Matrix Gla Protein (MGP).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  D-2F9
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-MGP Monoclonal Antibody (D-2F9) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Matrix Gla protein

Introduction

This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia.

Alternative Names

GIG36; MGLAP; NTI

Gene ID

4256

UniProt

P08493

Related Disease

Keutel syndrome (KTLS)

Subcellular Location

Secreted.

Cell Line Specificity

Group enriched

Function

Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.

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