Mouse Anti-MAPT Monoclonal Antibody

Subcat	Description	Isotype	Conjugate	Price
ASPC1249	Anti-MAPT Antibody	Mouse IgG2a, Kappa	None	$460	Add
ASPC1249-A	Anti-MAPT Antibody, APC	Mouse IgG2a, Kappa	APC	$980	Add
ASPC1249-B	Anti-MAPT Antibody, Biotin	Mouse IgG2a, Kappa	Biotin	$680	Add
ASPC1249-H	Anti-MAPT Antibody, HRP	Mouse IgG2a, Kappa	HRP	$600	Add
ASPC1249-P	Anti-MAPT Antibody, PE	Mouse IgG2a, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1249

Anti-MAPT Antibody

Mouse IgG2a, Kappa

None

$460

Add

ASPC1249-A

Anti-MAPT Antibody, APC

Mouse IgG2a, Kappa

APC

$980

Add

ASPC1249-B

Anti-MAPT Antibody, Biotin

Mouse IgG2a, Kappa

Biotin

$680

Add

ASPC1249-H

Anti-MAPT Antibody, HRP

Mouse IgG2a, Kappa

HRP

$600

Add

ASPC1249-P

Anti-MAPT Antibody, PE

Mouse IgG2a, Kappa

$1,180

Add

Mouse Anti-MAPT Monoclonal Antibody
- Product Description:
  
  The Anti-MAPT antibody is a mouse monoclonal antibody recommended for use in immunofluorescence, immunohistochemistry, enzyme-linked immunosorbent assay, western blot and other applications. This antibody specifically targets MAPT and demonstrates reactivity with human.
  
  Applications:
  
  Immunofluorescence, Immunohistochemistry, Enzyme-Linked Immunosorbent Assay, Western Blot
  
  Target:
  
  MAPT
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human MAPT.
  
  Immunogen:
  
  PF-tau protein.
  
  Epitope:
  
  ASQKRPSQR
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Mouse Anti-MAPT Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

MAPT

Protein Name

Microtubule-associated protein tau

Introduction

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Alternative Names

Microtubule Associated Protein Tau; G Protein Beta1/Gamma2 Subunit-Interacting Factor 1; Protein Phosphatase 1, Regulatory Subunit 103; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; MAPTL; MTBT1; TAU

Gene ID

4137

UniProt

P10636

Related Disease

Alzheimer disease

Subcellular Location

Cytoplasm, cytosol

Tissue Specificity

Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

Cell Line Specificity

Group enriched

Function

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity.

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