Anti-KLK3 Monoclonal Antibody (8G8F5)

Subcat	Description	Isotype	Conjugate	Price
ASPC1231	Anti-KLK3 Antibody (8G8F5)	Mouse IgG1, Kappa	None	$460	Add
ASPC1231-A	Anti-KLK3 Antibody (8G8F5), APC	Mouse IgG1, Kappa	APC	$980	Add
ASPC1231-B	Anti-KLK3 Antibody (8G8F5), Biotin	Mouse IgG1, Kappa	Biotin	$680	Add
ASPC1231-H	Anti-KLK3 Antibody (8G8F5), HRP	Mouse IgG1, Kappa	HRP	$600	Add
ASPC1231-P	Anti-KLK3 Antibody (8G8F5), PE	Mouse IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1231

Anti-KLK3 Antibody (8G8F5)

Mouse IgG1, Kappa

None

$460

Add

ASPC1231-A

Anti-KLK3 Antibody (8G8F5), APC

Mouse IgG1, Kappa

APC

$980

Add

ASPC1231-B

Anti-KLK3 Antibody (8G8F5), Biotin

Mouse IgG1, Kappa

Biotin

$680

Add

ASPC1231-H

Anti-KLK3 Antibody (8G8F5), HRP

Mouse IgG1, Kappa

HRP

$600

Add

ASPC1231-P

Anti-KLK3 Antibody (8G8F5), PE

Mouse IgG1, Kappa

$1,180

Add

Anti-KLK3 Monoclonal Antibody (8G8F5)
- Product Description:
  
  The Anti-KLK3 antibody is a mouse monoclonal antibody recommended for use in enzyme-linked immunosorbent assay and other applications. This antibody specifically targets KLK3 and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  KLK3
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human KLK3.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  8G8F5
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-KLK3 Monoclonal Antibody (8G8F5) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

KLK3

Protein Name

Prostate-specific antigen

Introduction

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Alternative Names

APS; KLK2A1; PSA; hK3

Gene ID

354

UniProt

P07288

Subcellular Location

Secreted.

Cell Line Specificity

Cancer enriched

Function

Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.