Anti-KIT Monoclonal Antibody (79D)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC121	Anti-KIT Antibody (79D)	Human IgG1, Kappa		None	$460	In stock	Add
ASPC121-P	Anti-KIT Antibody (79D), PE	Human IgG1, Kappa		PE	$1,180	2-3 weeks	Add
ASPC121-A	Anti-KIT Antibody (79D), APC	Human IgG1, Kappa		APC	$980	2-3 weeks	Add
ASPC121-H	Anti-KIT Antibody (79D), HRP	Human IgG1, Kappa		HRP	$600	2-3 weeks	Add
ASPC121-B	Anti-KIT Antibody (79D), Biotin	Human IgG1, Kappa		Biotin	$680	2-3 weeks	Add
ASPC121-4	Anti-KIT Antibody (79D), Fc Silenced	Human IgG1, Kappa	Fc Silenced	None	$980	4-6 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC121

Anti-KIT Antibody (79D)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC121-P

Anti-KIT Antibody (79D), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC121-A

Anti-KIT Antibody (79D), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC121-H

Anti-KIT Antibody (79D), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC121-B

Anti-KIT Antibody (79D), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

ASPC121-4

Anti-KIT Antibody (79D), Fc Silenced

Human IgG1, Kappa

Fc Silenced

None

$980

4-6 weeks

Add

Anti-KIT Monoclonal Antibody (79D)
- Product Description:
  
  The 79D antibody is a monoclonal antibody that specifically targets the membrane-proximal Ig-like domain 4 of human KIT protein, a receptor tyrosine kinase. KIT, also known as CD117, is a transmembrane protein that plays vital roles in various cellular processes, including cell differentiation, proliferation, and survival.
  
  Applications:
  
  Inhibition, Immunoprecipitation, Surface Plasmon Resonance, Western Blot
  
  Source:
  
  Human
  
  Target:
  
  KIT
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human KIT
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  79D
  
  Isotype:
  
  Human IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-KIT Monoclonal Antibody (79D) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

KIT

Protein Name

Mast/stem cell growth factor receptor Kit

Molecular Family

CD Molecules

Introduction

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative Names

KIT Proto-Oncogene Receptor Tyrosine Kinase; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Tyrosine-Protein Kinase Kit; Piebald Trait Protein; Proto-Oncogene C-Kit; EC 2.7.10.1; P145 C-Kit; SCFR; PBT

Gene ID

3815

UniProt

P10721

Related Disease

Piebald trait (PBT)

Subcellular Location

Plasma membrane

Tissue Specificity

[Isoform 3]: In testis, detected in spermatogonia in the basal layer and in interstitial Leydig cells but not in Sertoli cells or spermatocytes inside the seminiferous tubules (at protein level). Expression is maintained in ejaculated spermatozoa (at protein level).

Cell Type

Embryonic Stem Cells, Hematopoietic stem and progenitors, Leukemia, Mast cells, Mesenchymal Stem Cells

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