Anti-KEL Monoclonal Antibody (MIMA-8)

Anti-KEL Monoclonal Antibody (MIMA-8)

Cat No: ASPC049

Summary
Host Species:
Human
Species Reactivity:
Human, Mouse
Applications:
Flow Cytometry
Clone ID:
MIMA-8
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC049 Anti-KEL Antibody (MIMA-8) Human IgG1, Kappa None $460 4-6 weeks
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ASPC049-P Anti-KEL Antibody (MIMA-8), PE Human IgG1, Kappa PE $1,180 2-3 weeks
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ASPC049-A Anti-KEL Antibody (MIMA-8), APC Human IgG1, Kappa APC $980 2-3 weeks
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ASPC049-H Anti-KEL Antibody (MIMA-8), HRP Human IgG1, Kappa HRP $600 2-3 weeks
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ASPC049-B Anti-KEL Antibody (MIMA-8), Biotin Human IgG1, Kappa Biotin $680 2-3 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-KEL Monoclonal Antibody (MIMA-8)
    • Product Description:
      The MIMA-8 antibody is a monoclonal antibody specifically developed to target the Kell protein on the surface of human erythrocytes (red blood cells). The Kell protein is a crucial component of one of the major blood group systems in humans, known as the Kell blood group system.
      Applications:
      Flow Cytometry
      Source:
      Mouse
      Target:
      KEL
      Specificity:
      Kell protein
      Immunogen:
      Human KEL protein.
      Clonality:
      Monoclonal
      Clone ID:
      MIMA-8
      Isotype:
      Human IgG1, Kappa
      Purification:
      The antibody was purified by Protein A.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for customized product form or formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-KEL Monoclonal Antibody (MIMA-8) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
KEL
Protein Name
Kell blood group glycoprotein
Introduction
This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.
Alternative Names
ECE3; Kell; CD238
UniProt
Subcellular Location
Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol
Tissue Specificity
Expressed at high levels in erythrocytes and testis (in Sertoli cells), and, at lower levels, in skeletal muscle, tonsils (in follicular dendritic cells), lymph node, spleen and appendix (at protein level). Also expressed in many adult and fetal nonerythroid tissues, including brain, spleen, lymph nodes and bone marrow.
Cell Type
Tregs
Function
Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3.
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