Anti-KDR Monoclonal Antibody (10B12)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC413	Anti-KDR Antibody (10B12)	Mouse IgG1, Kappa	None	$460	In stock	Add
ASPC413-P	Anti-KDR Antibody (10B12), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC413-A	Anti-KDR Antibody (10B12), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC413-H	Anti-KDR Antibody (10B12), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC413-B	Anti-KDR Antibody (10B12), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC413

Anti-KDR Antibody (10B12)

Mouse IgG1, Kappa

None

$460

In stock

Add

ASPC413-P

Anti-KDR Antibody (10B12), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC413-A

Anti-KDR Antibody (10B12), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC413-H

Anti-KDR Antibody (10B12), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC413-B

Anti-KDR Antibody (10B12), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-KDR Monoclonal Antibody (10B12)
- Product Description:
  
  The Anti-KDR antibody is a mouse monoclonal antibody recommended for use in inhibition and other applications. This antibody specifically targets KDR and demonstrates reactivity with human.
  
  Applications:
  
  Inhibition
  
  Target:
  
  KDR
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human VEGFR-2.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  10B12
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-KDR Monoclonal Antibody (10B12) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

KDR

Protein Name

Vascular endothelial growth factor receptor 2

Introduction

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Alternative Names

FLK1; CD309; VEGFR; VEGFR2

Gene ID

3791

UniProt

P35968

Molecule Mass

CD Molecules

Related Disease

Hemangioma, capillary infantile (HCI)

Subcellular Location

Cell junction

Tissue Specificity

Detected in cornea (at protein level). Widely expressed.

Cell Line Specificity

Cancer enriched

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