Anti-KAZALD1 Monoclonal Antibody (F-9F1)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1099	Anti-KAZALD1 Antibody (F-9F1)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1099

Anti-KAZALD1 Antibody (F-9F1)

Mouse IgG

None

$460

Add

Anti-KAZALD1 Monoclonal Antibody (F-9F1)
- Product Description:
  
  The Anti-KAZALD1 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human KAZALD1.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  KAZALD1
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Kazal Type Serine Peptidase Inhibitor Domain 1 (KAZALD1).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  F-9F1
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-KAZALD1 Monoclonal Antibody (F-9F1) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Kazal-type serine protease inhibitor domain-containing protein 1

Introduction

This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. The protein contains an insulin growth factor-binding domain in its N-terminal region, a Kazal-type serine protease inhibitor and follistatin-like domain in its central region, and an immunoglobulin-like domain in its C-terminal region. Studies of the mouse ortholog suggest that this protein may function in bone development and bone regeneration. This gene is hypomethylated and over-expressed in high-grade glioma compared to low-grade glioma, and thus the hypomethylated gene may be associated with cell proliferation and the shorter survival of patients with high-grade glioma. It is also one of numerous genes found to be deleted in a novel 5.54 Mb interstitial deletion, which is associated with multiple congenital anomalies. Alternative splicing results in multiple transcript variants.

Alternative Names

BONO1; FKSG28; FKSG40; IGFBP-rP10

Gene ID

81621

UniProt

Q96I82

Subcellular Location

Secreted, extracellular space, extracellular matrix

Cell Line Specificity

Cancer enhanced

Function

Involved in the proliferation of osteoblasts during bone formation and bone regeneration. Promotes matrix assembly (By similarity).