Anti-ITGB2 Monoclonal Antibody (H52)

Subcat	Description	Isotype	Conjugate	Price
ASPC074	Anti-ITGB2 Antibody (H52)	Human IgG1, Kappa	None	$460	Add
ASPC074-P	Anti-ITGB2 Antibody (H52), PE	Human IgG1, Kappa	PE	$1,180	Add
ASPC074-A	Anti-ITGB2 Antibody (H52), APC	Human IgG1, Kappa	APC	$980	Add
ASPC074-H	Anti-ITGB2 Antibody (H52), HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC074-B	Anti-ITGB2 Antibody (H52), Biotin	Human IgG1, Kappa	Biotin	$680	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC074

Anti-ITGB2 Antibody (H52)

Human IgG1, Kappa

None

$460

Add

ASPC074-P

Anti-ITGB2 Antibody (H52), PE

Human IgG1, Kappa

$1,180

Add

ASPC074-A

Anti-ITGB2 Antibody (H52), APC

Human IgG1, Kappa

APC

$980

Add

ASPC074-H

Anti-ITGB2 Antibody (H52), HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC074-B

Anti-ITGB2 Antibody (H52), Biotin

Human IgG1, Kappa

Biotin

$680

Add

Anti-ITGB2 Monoclonal Antibody (H52)
- Product Description:
  
  The H52 antibody is a monoclonal antibody that specifically reacts with a disulfide-bonded loop within the ITGB2 protein.
  
  Applications:
  
  Immunoprecipitation, Blocking, Flow Cytometry
  
  Source:
  
  Mouse
  
  Target:
  
  ITGB2
  
  Target Species:
  
  Human
  
  Specificity:
  
  ITGB2
  
  Immunogen:
  
  Adherent splenic cells isolated from human
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  H52
  
  Isotype:
  
  Human IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ITGB2 Monoclonal Antibody (H52) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

ITGB2

Protein Name

Integrin beta-2

Molecular Family

Adhesion Molecules, CD Molecules

Introduction

This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

Alternative Names

Integrin Subunit Beta 2

Gene ID

3689

UniProt

P05107

Related Disease

Leukocyte adhesion deficiency 1 (LAD1)

Subcellular Location

Plasma membrane,Rods & Rings

Tissue Specificity

Leukocytes (PubMed:23775590). Expressed in neutrophils (at protein level) (PubMed:21193407, PubMed:28807980).

Cell Type

Leukocytes, Tregs

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