Anti-ITGAX Monoclonal Antibody (N418)

Subcat	Description	Isotype	Conjugate	Price
ASPC1219	Anti-ITGAX Antibody (N418)	Hamster IgG, Kappa	None	$460	Add
ASPC1219-A	Anti-ITGAX Antibody (N418), APC	Hamster IgG, Kappa	APC	$980	Add
ASPC1219-B	Anti-ITGAX Antibody (N418), Biotin	Hamster IgG, Kappa	Biotin	$680	Add
ASPC1219-H	Anti-ITGAX Antibody (N418), HRP	Hamster IgG, Kappa	HRP	$600	Add
ASPC1219-P	Anti-ITGAX Antibody (N418), PE	Hamster IgG, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1219

Anti-ITGAX Antibody (N418)

Hamster IgG, Kappa

None

$460

Add

ASPC1219-A

Anti-ITGAX Antibody (N418), APC

Hamster IgG, Kappa

APC

$980

Add

ASPC1219-B

Anti-ITGAX Antibody (N418), Biotin

Hamster IgG, Kappa

Biotin

$680

Add

ASPC1219-H

Anti-ITGAX Antibody (N418), HRP

Hamster IgG, Kappa

HRP

$600

Add

ASPC1219-P

Anti-ITGAX Antibody (N418), PE

Hamster IgG, Kappa

$1,180

Add

Anti-ITGAX Monoclonal Antibody (N418)
- Product Description:
  
  The Anti-ITGAX antibody is a hamster monoclonal antibody recommended for use in enzyme-linked immunosorbent assay and other applications. This antibody specifically targets ITGAX and demonstrates reactivity with human and mouse.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay
  
  Source:
  
  Hamster
  
  Target:
  
  ITGAX
  
  Specificity:
  
  This antibody reacts with ITGAX.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  N418
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ITGAX Monoclonal Antibody (N418) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

ITGAX

Protein Name

Integrin alpha-X

Introduction

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

Alternative Names

CD11C; SLEB6

Gene ID

3687

UniProt

P20702

Subcellular Location

Membrane

Tissue Specificity

Predominantly expressed in monocytes and granulocytes.

Cell Line Specificity

Cancer enhanced

Function

Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

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