Anti-ITGA6 Monoclonal Antibody (C-4E11)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1083	Anti-ITGA6 Antibody (C-4E11)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1083

Anti-ITGA6 Antibody (C-4E11)

Mouse IgG

None

$460

Add

Anti-ITGA6 Monoclonal Antibody (C-4E11)
- Product Description:
  
  The Anti-ITGA6 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human ITGA6.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  ITGA6
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Integrin Subunit Alpha 6 (ITGA6).
  
  Immunogen:
  
  Recombinant ITGa6 protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  C-4E11
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ITGA6 Monoclonal Antibody (C-4E11) Applications
- Recommended Dilution:
  
  Western Blot: 0.5-2 µg/mL
  Immunohistochemistry: 5-20 µg/mL
  Immunocytochemistry: 5-20 µg/mL
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Integrin alpha-6

Introduction

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.

Alternative Names

CD49fB; VLA-6; ITGA6

Gene ID

3655

UniProt

P23229

Related Disease

Epidermolysis bullosa, junctional 6, with pyloric atresia (JEB6)

Subcellular Location

Cell membrane

Cell Line Specificity

Low cancer specificity