Anti-ITGA4 Monoclonal Antibody (HP1/2)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price
ASPC129	Anti-ITGA4 Antibody (HP1/2)	Human IgG1, Kappa		None	$460	Add
ASPC129-1	Anti-ITGA4 Antibody (HP1/2), Fab fragment	Human Fab	His tag	None	$460	Add
ASPC129-P	Anti-ITGA4 Antibody (HP1/2), PE	Human IgG1, Kappa		PE	$1,180	Add
ASPC129-A	Anti-ITGA4 Antibody (HP1/2), APC	Human IgG1, Kappa		APC	$980	Add
ASPC129-H	Anti-ITGA4 Antibody (HP1/2), HRP	Human IgG1, Kappa		HRP	$600	Add
ASPC129-B	Anti-ITGA4 Antibody (HP1/2), Biotin	Human IgG1, Kappa		Biotin	$680	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC129

Anti-ITGA4 Antibody (HP1/2)

Human IgG1, Kappa

None

$460

Add

ASPC129-1

Anti-ITGA4 Antibody (HP1/2), Fab fragment

Human Fab

His tag

None

$460

Add

ASPC129-P

Anti-ITGA4 Antibody (HP1/2), PE

Human IgG1, Kappa

$1,180

Add

ASPC129-A

Anti-ITGA4 Antibody (HP1/2), APC

Human IgG1, Kappa

APC

$980

Add

ASPC129-H

Anti-ITGA4 Antibody (HP1/2), HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC129-B

Anti-ITGA4 Antibody (HP1/2), Biotin

Human IgG1, Kappa

Biotin

$680

Add

Anti-ITGA4 Monoclonal Antibody (HP1/2)
- Product Description:
  
  HP1/2 is a monoclonal antibody that specifically recognizes human CD49d. This integrin is a component of two important heterodimers: α4β1 (VLA-4) and α4β7, both of which play critical roles in cell adhesion and immune responses. This antibody also cross-reacts with α4β7.
  
  Applications:
  
  Inhibition, Immunoprecipitation, Blocking, Flow Cytometry
  
  Source:
  
  Mouse
  
  Target:
  
  ITGA4
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human integrin alpha 4/CD49D
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  HP1/2
  
  Isotype:
  
  Human IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ITGA4 Monoclonal Antibody (HP1/2) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

ITGA4

Protein Name

Integrin alpha-4

Molecular Family

Adhesion Molecules, CD Molecules

Introduction

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.

Alternative Names

Integrin Subunit Alpha 4; ITGA4

Gene ID

3676

UniProt

P13612

Subcellular Location

Plasma membrane

Cell Type

B cells, Dendritic cells, Eosinophils, Mast cells, Monocytes, NK cells, T cells, Thymocytes, Tregs

Customer Reviews

There are no reviews for Product Name.

Submit a review and receive an Amazon gift card.

Publications

There are no publications for Product Name.

If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward