Anti-ITGA2 Monoclonal Antibody - Amerigo Scientific

Subcat	Description	Isotype	Conjugate	Price
ASPC1215	Anti-ITGA2 Antibody	Human IgG1, Kappa	None	$460	Add
ASPC1215-A	Anti-ITGA2 Antibody, APC	Human IgG1, Kappa	APC	$980	Add
ASPC1215-B	Anti-ITGA2 Antibody, Biotin	Human IgG1, Kappa	Biotin	$680	Add
ASPC1215-H	Anti-ITGA2 Antibody, HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC1215-P	Anti-ITGA2 Antibody, PE	Human IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1215

Anti-ITGA2 Antibody

Human IgG1, Kappa

None

$460

Add

ASPC1215-A

Anti-ITGA2 Antibody, APC

Human IgG1, Kappa

APC

$980

Add

ASPC1215-B

Anti-ITGA2 Antibody, Biotin

Human IgG1, Kappa

Biotin

$680

Add

ASPC1215-H

Anti-ITGA2 Antibody, HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC1215-P

Anti-ITGA2 Antibody, PE

Human IgG1, Kappa

$1,180

Add

Anti-ITGA2 Monoclonal Antibody
- Product Description:
  
  The Anti-ITGA2 antibody is a human monoclonal antibody recommended for use in flow cytometry, enzyme-linked immunosorbent assay, blocking, functional assay and other applications. This antibody specifically targets ITGA2 and demonstrates reactivity with Rat, Human, Rhesus Monkey, Cynomolgus Monkey.
  
  Applications:
  
  Flow Cytometry, Enzyme-Linked Immunosorbent Assay, Blocking, Functional Assay
  
  Target:
  
  ITGA2
  
  Specificity:
  
  This antibody reacts with ITGA2.
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ITGA2 Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

ITGA2

Protein Name

Integrin alpha-2

Introduction

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Alternative Names

BR; CD49B; GPIa; HPA-5; VLA-2; VLAA2

Gene ID

3673

UniProt

P17301

Subcellular Location

Membrane

Cell Line Specificity

Low cancer specificity

Function

Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.; (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A.

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