Anti-Integrin ανβ8 Monoclonal Antibody (2F9)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC821	Anti-Integrin ανβ8 Antibody (2F9)	Mouse IgG2a, Kappa		None	$460	In stock	Add
ASPC821-1	Anti-Integrin ανβ8 Antibody (2F9), scFv fragment	Mouse scFv	His tag	None	$460	In stock	Add
ASPC821-P	Anti-Integrin ανβ8 Antibody (2F9), PE	Mouse IgG2a, Kappa		PE	$1,180	2-3 weeks	Add
ASPC821-A	Anti-Integrin ανβ8 Antibody (2F9), APC	Mouse IgG2a, Kappa		APC	$980	2-3 weeks	Add
ASPC821-H	Anti-Integrin ανβ8 Antibody (2F9), HRP	Mouse IgG2a, Kappa		HRP	$600	2-3 weeks	Add
ASPC821-B	Anti-Integrin ανβ8 Antibody (2F9), Biotin	Mouse IgG2a, Kappa		Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC821

Anti-Integrin ανβ8 Antibody (2F9)

Mouse IgG2a, Kappa

None

$460

In stock

Add

ASPC821-1

Anti-Integrin ανβ8 Antibody (2F9), scFv fragment

Mouse scFv

His tag

None

$460

In stock

Add

ASPC821-P

Anti-Integrin ανβ8 Antibody (2F9), PE

Mouse IgG2a, Kappa

$1,180

2-3 weeks

Add

ASPC821-A

Anti-Integrin ανβ8 Antibody (2F9), APC

Mouse IgG2a, Kappa

APC

$980

2-3 weeks

Add

ASPC821-H

Anti-Integrin ανβ8 Antibody (2F9), HRP

Mouse IgG2a, Kappa

HRP

$600

2-3 weeks

Add

ASPC821-B

Anti-Integrin ανβ8 Antibody (2F9), Biotin

Mouse IgG2a, Kappa

Biotin

$680

2-3 weeks

Add

Anti-Integrin ανβ8 Monoclonal Antibody (2F9)
- Product Description:
  
  The Anti-Integrin ανβ8 antibody is a mouse monoclonal antibody recommended for use in ELISA, blocking and other applications. This antibody specifically targets Integrin ανβ8 and demonstrates reactivity with human, mouse.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Blocking, Western Blot
  
  Target:
  
  Integrin ανβ8
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human ανβ8.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  2F9
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-Integrin ανβ8 Monoclonal Antibody (2F9) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Introduction

In general, integrins are adhesion molecules and mediate the attachment of cells to extracellular matrix proteins. Integrin avp8 binds to the LAP of TGF-β and mediates the activation of TGF-βΙ and 3. Integrin v'PS-mediated activation of TGF-β is required for in vivo activation of TGF-β, thus αvβ8 is a gatekeeper of TGF-β function. Integrin cxvβS is expressed in normal epithelia, mesenchymal cells, and neuronal tissues. The integrin β8 has been associated with forkhead box P3 (Foxp3)-positive T cells and T-regulatoryspecific epigenetic remodeling. FoxP3 is a transcription factor involved in the development of T-regulatory (Treg) cells. Human and mouse effector Treg cells express functional TGFP-activating integrin ανβ8.

Alternative Names

Integrin ανβ8; Integrin alpha V beta 8

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