Anti-INS Monoclonal Antibody (mAb13)

Anti-INS Monoclonal Antibody (mAb13)

Cat No: ASPC117

Summary
Host Species:
Human
Species Reactivity:
Human
Applications:
Enzyme-Linked Immunosorbent Assay
Clone ID:
mAb13
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC117 Anti-INS Antibody (mAb13) Human IgG1, Kappa None $460 In stock
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ASPC117-P Anti-INS Antibody (mAb13), PE Human IgG1, Kappa PE $1,180 2-3 weeks
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ASPC117-A Anti-INS Antibody (mAb13), APC Human IgG1, Kappa APC $980 2-3 weeks
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ASPC117-H Anti-INS Antibody (mAb13), HRP Human IgG1, Kappa HRP $600 2-3 weeks
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ASPC117-B Anti-INS Antibody (mAb13), Biotin Human IgG1, Kappa Biotin $680 2-3 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-INS Monoclonal Antibody (mAb13)
    • Product Description:
      mAb13 is a monoclonal antibody that specifically reacts with human insulin, a critical peptide hormone involved in the regulation of blood glucose levels.
      Applications:
      Enzyme-Linked Immunosorbent Assay
      Source:
      Human
      Target:
      INS
      Target Species:
      Human
      Specificity:
      Human insulin
      Clonality:
      Monoclonal
      Clone ID:
      mAb13
      Isotype:
      Human IgG1, Kappa
      Purification:
      The antibody was purified by Protein A.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for customized product form or formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-INS Monoclonal Antibody (mAb13) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
INS
Protein Name
Insulin
Introduction
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
Alternative Names
Insulin; INS
Gene ID
UniProt
Function
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
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