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Anti-IL4 Monoclonal Antibody (15B5)
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Product Description:The Anti-IL4 antibody is a human monoclonal antibody recommended for use in ELISA, western blot and other applications. This antibody specifically targets IL4 and demonstrates reactivity with human.Applications:Enzyme-Linked Immunosorbent Assay, Western BlotTarget:IL4Target Species:HumanSpecificity:This antibody reacts with human IL4.Clonality:MonoclonalClone ID:15B5Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEAggregation:<5% as determined by SECForm:LiquidEndotoxin:Please contact us for more information.Formulation:Contact us for custom product formulation.Preservative:BSA and Azide free.Stabilizer:NoneShipping:Shipped at 4°C.Storage:This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-IL4 Monoclonal Antibody (15B5) Applications
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Note:Optimal dilutions/concentrations should be determined by the end user.
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Gene Symbol
IL4
Protein Name
Interleukin-4
Introduction
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation. This cytokine has been reported to promote resolution of neutrophil-mediated acute lung injury. In an allergic response, IL-4 has an essential role in the production of allergen-specific immunoglobin (Ig) E.
Alternative Names
BSF1; IL-4; BCGF1; BSF-1; BCGF-1
Gene ID
UniProt
Molecule Mass
Cytokines/Chemokines
Related Disease
Ischemic stroke (ISCHSTR)
Subcellular Location
Secreted.
Cell Line Specificity
Cancer enhanced
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