Anti-IL20 Monoclonal Antibody (Fletikumab)

Anti-IL20 Monoclonal Antibody (Fletikumab)

Cat No: ASPC1195

Summary
Host Species:
Human
Species Reactivity:
Human, Cynomolgus Monkey, Mouse
Applications:
Enzyme-Linked Immunosorbent Assay, Western Blot, Functional Assay, Neutralization, Inhibition
Clone ID:
Fletikumab
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASPC1195 Anti-IL20 Antibody (Fletikumab) Human IgG4, Kappa None $460
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ASPC1195-A Anti-IL20 Antibody (Fletikumab), APC Human IgG4, Kappa APC $980
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ASPC1195-B Anti-IL20 Antibody (Fletikumab), Biotin Human IgG4, Kappa Biotin $680
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ASPC1195-H Anti-IL20 Antibody (Fletikumab), HRP Human IgG4, Kappa HRP $600
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ASPC1195-P Anti-IL20 Antibody (Fletikumab), PE Human IgG4, Kappa PE $1,180
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-IL20 Monoclonal Antibody (Fletikumab)
    • Product Description:
      The Anti-IL20 antibody is a human monoclonal antibody recommended for use in enzyme-linked immunosorbent assay, western blot, functional assay, neutralization, inhibition and other applications. This antibody specifically targets IL20 and demonstrates reactivity with Human, Cynomolgus Monkey, Mouse.
      Applications:
      Enzyme-Linked Immunosorbent Assay, Western Blot, Functional Assay, Neutralization, Inhibition
      Target:
      IL20
      Specificity:
      This antibody reacts with IL20.
      Immunogen:
      Human interleukin-20 (IL-20).
      Clonality:
      Monoclonal
      Clone ID:
      Fletikumab
      Clone Synonyms:
      h15D2
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-IL20 Monoclonal Antibody (Fletikumab) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
IL20
Protein Name
Interleukin-20
Introduction
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
Alternative Names
Interleukin 20; IL20
Gene ID
UniProt
Subcellular Location
Secreted
Tissue Specificity
Expressed in most tissues and five major cell types: epithelial cells (primarily skin, buccal mucosa, tongue, nasal mucosa, lung, ureter, breast, prostate, fallopian tube, and adrenal gland), myoepithelial cells (mainly prostate), endothelial cells (mainly in small vessels or capillaries), macrophages, and skeletal muscle. Isoform 2 was detected in the lung tissue only.
Cell Line Specificity
Cancer enriched
Function
Proinflammatory and angiogenic cytokine that may be involved in epidermal function and psoriasis. Angiogenic and proliferative activities are antagonized by IL10. May act through STAT3.
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