Anti-IL18 Monoclonal Antibody (11G5)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC495	Anti-IL18 Antibody (11G5)	Rat IgG1, Kappa		None	$460	In stock	Add
ASPC495-1	Anti-IL18 Antibody (11G5), scFv fragment	Rat scFv	His tag	None	$460	In stock	Add
ASPC495-P	Anti-IL18 Antibody (11G5), PE	Rat IgG1, Kappa		PE	$1,180	2-3 weeks	Add
ASPC495-A	Anti-IL18 Antibody (11G5), APC	Rat IgG1, Kappa		APC	$980	2-3 weeks	Add
ASPC495-H	Anti-IL18 Antibody (11G5), HRP	Rat IgG1, Kappa		HRP	$600	2-3 weeks	Add
ASPC495-B	Anti-IL18 Antibody (11G5), Biotin	Rat IgG1, Kappa		Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC495

Anti-IL18 Antibody (11G5)

Rat IgG1, Kappa

None

$460

In stock

Add

ASPC495-1

Anti-IL18 Antibody (11G5), scFv fragment

Rat scFv

His tag

None

$460

In stock

Add

ASPC495-P

Anti-IL18 Antibody (11G5), PE

Rat IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC495-A

Anti-IL18 Antibody (11G5), APC

Rat IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC495-H

Anti-IL18 Antibody (11G5), HRP

Rat IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC495-B

Anti-IL18 Antibody (11G5), Biotin

Rat IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-IL18 Monoclonal Antibody (11G5)
- Product Description:
  
  The Anti-IL18 antibody is a rat monoclonal antibody recommended for use in ELISA, western blot, dot blot and other applications. This antibody specifically targets IL18 and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Western Blot, Dot Blot
  
  Target:
  
  IL18
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human IL18.
  
  Immunogen:
  
  Human Interleukin 18
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  11G5
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-IL18 Monoclonal Antibody (11G5) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

IL18

Protein Name

Interleukin-18

Introduction

The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm.

Alternative Names

IGIF; IL-18; IL-1g; IL1F4

Gene ID

3606

UniProt

Q14116

Molecule Mass

Cytokines

Subcellular Location

Cytoplasm, cytosol

Tissue Specificity

[Isoform 2]: Expressed in ovarian carcinoma but undetectable in normal ovarian epithelial cells. Resistant to proteolytic activation by caspase-1 and -4.

Cell Line Specificity

Low cancer specificity

Function

Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.

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