Anti-IL13 Monoclonal Antibody (CNTO607)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC125	Anti-IL13 Antibody (CNTO607)	Human IgG1, Lambda		None	$460	In stock	Add
ASPC125-P	Anti-IL13 Antibody (CNTO607), PE	Human IgG1, Lambda		PE	$1,180	2-3 weeks	Add
ASPC125-A	Anti-IL13 Antibody (CNTO607), APC	Human IgG1, Lambda		APC	$980	2-3 weeks	Add
ASPC125-H	Anti-IL13 Antibody (CNTO607), HRP	Human IgG1, Lambda		HRP	$600	2-3 weeks	Add
ASPC125-B	Anti-IL13 Antibody (CNTO607), Biotin	Human IgG1, Lambda		Biotin	$680	2-3 weeks	Add
ASPC125-4	Anti-IL13 Antibody (CNTO607), Fc Silenced	Human IgG1, Lambda	Fc Silenced	None	$980	4-6 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC125

Anti-IL13 Antibody (CNTO607)

Human IgG1, Lambda

None

$460

In stock

Add

ASPC125-P

Anti-IL13 Antibody (CNTO607), PE

Human IgG1, Lambda

$1,180

2-3 weeks

Add

ASPC125-A

Anti-IL13 Antibody (CNTO607), APC

Human IgG1, Lambda

APC

$980

2-3 weeks

Add

ASPC125-H

Anti-IL13 Antibody (CNTO607), HRP

Human IgG1, Lambda

HRP

$600

2-3 weeks

Add

ASPC125-B

Anti-IL13 Antibody (CNTO607), Biotin

Human IgG1, Lambda

Biotin

$680

2-3 weeks

Add

ASPC125-4

Anti-IL13 Antibody (CNTO607), Fc Silenced

Human IgG1, Lambda

Fc Silenced

None

$980

4-6 weeks

Add

Anti-IL13 Monoclonal Antibody (CNTO607)
- Product Description:
  
  The CNTO607 antibody is a neutralizing monoclonal antibody that targets a critical epitope on IL-13, blocking its interaction with IL-4Rα and IL-13Rα1 receptors.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Neutralization
  
  Source:
  
  Human
  
  Target:
  
  IL13
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human interleukin-13
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  CNTO607
  
  Isotype:
  
  Human IgG1, Lambda
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-IL13 Monoclonal Antibody (CNTO607) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

IL13

Protein Name

Interleukin-13

Molecular Family

Cytokines/Chemokines

Introduction

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Alternative Names

Interleukin 13

Gene ID

3596

UniProt

P35225

Related Disease

Allergic rhinitis (ALRH)

Cell Type

Tregs

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