Anti-IFNAR1 Monoclonal Antibody (64G12)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC079	Anti-IFNAR1 Antibody (64G12)	Mouse IgG1, Kappa	None	$460	In stock	Add
ASPC079-P	Anti-IFNAR1 Antibody (64G12), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC079-A	Anti-IFNAR1 Antibody (64G12), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC079-H	Anti-IFNAR1 Antibody (64G12), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC079-B	Anti-IFNAR1 Antibody (64G12), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC079

Anti-IFNAR1 Antibody (64G12)

Mouse IgG1, Kappa

None

$460

In stock

Add

ASPC079-P

Anti-IFNAR1 Antibody (64G12), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC079-A

Anti-IFNAR1 Antibody (64G12), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC079-H

Anti-IFNAR1 Antibody (64G12), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC079-B

Anti-IFNAR1 Antibody (64G12), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-IFNAR1 Monoclonal Antibody (64G12)
- Product Description:
  
  The 64G12 antibody is a monoclonal antibody that specifically targets the extracellular domain of the human Type I Interferon Receptor (IFN-R). The 64G12 antibody has neutralizing capacity, meaning it can inhibit the biological effects of Type I IFNs.
  
  Applications:
  
  Inhibition, Immunoprecipitation, Enzyme-Linked Immunosorbent Assay, Western Blot, Flow Cytometry, Immunofluorescence
  
  Source:
  
  Mouse
  
  Target:
  
  IFNAR1
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human IFNAR1
  
  Immunogen:
  
  Recombinant soluble interferon receptors
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  64G12
  
  Isotype:
  
  Mouse IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-IFNAR1 Monoclonal Antibody (64G12) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

IFNAR1

Protein Name

Interferon alpha/beta receptor 1

Introduction

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.

Alternative Names

Interferon Alpha And Beta Receptor Subunit 1

Gene ID

3454

UniProt

P17181

Related Disease

Immunodeficiency 106, susceptibility to viral infections (IMD106)

Tissue Specificity

IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.

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