Anti-ICAM3 Monoclonal Antibody (A-12A12)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C990	Anti-ICAM3 Antibody (A-12A12)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C990

Anti-ICAM3 Antibody (A-12A12)

Mouse IgG

None

$460

Add

Anti-ICAM3 Monoclonal Antibody (A-12A12)
- Product Description:
  
  The Anti-ICAM3 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human ICAM3.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  ICAM3
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Intercellular Adhesion Molecule 3 (ICAM3).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  A-12A12
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ICAM3 Monoclonal Antibody (A-12A12) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Intercellular adhesion molecule 3

Introduction

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative Names

CD50; CDW50; ICAM-R

Gene ID

3385

UniProt

P32942

Subcellular Location

Membrane; Single-pass type I membrane protein.

Tissue Specificity

Leukocytes.

Cell Line Specificity

Cancer enhanced