Anti-IAPP Monoclonal Antibody (15H7)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC384	Anti-IAPP Antibody (15H7)	Human IgG1, Kappa		None	$460	4-6 weeks	Add
ASPC384-1	Anti-IAPP Antibody (15H7), Fab fragment	Human Fab	His tag	None	$460	In stock	Add
ASPC384-P	Anti-IAPP Antibody (15H7), PE	Human IgG1, Kappa		PE	$1,180	4-6 weeks	Add
ASPC384-A	Anti-IAPP Antibody (15H7), APC	Human IgG1, Kappa		APC	$980	4-6 weeks	Add
ASPC384-H	Anti-IAPP Antibody (15H7), HRP	Human IgG1, Kappa		HRP	$600	4-6 weeks	Add
ASPC384-B	Anti-IAPP Antibody (15H7), Biotin	Human IgG1, Kappa		Biotin	$680	4-6 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC384

Anti-IAPP Antibody (15H7)

Human IgG1, Kappa

None

$460

4-6 weeks

Add

ASPC384-1

Anti-IAPP Antibody (15H7), Fab fragment

Human Fab

His tag

None

$460

In stock

Add

ASPC384-P

Anti-IAPP Antibody (15H7), PE

Human IgG1, Kappa

$1,180

4-6 weeks

Add

ASPC384-A

Anti-IAPP Antibody (15H7), APC

Human IgG1, Kappa

APC

$980

4-6 weeks

Add

ASPC384-H

Anti-IAPP Antibody (15H7), HRP

Human IgG1, Kappa

HRP

$600

4-6 weeks

Add

ASPC384-B

Anti-IAPP Antibody (15H7), Biotin

Human IgG1, Kappa

Biotin

$680

4-6 weeks

Add

Anti-IAPP Monoclonal Antibody (15H7)
- Product Description:
  
  The Anti-IAPP antibody is a human monoclonal antibody recommended for use in ELISA and other applications. This antibody specifically targets IAPP and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  IAPP
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human IAPP.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  15H7
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-IAPP Monoclonal Antibody (15H7) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

IAPP

Protein Name

Islet amyloid polypeptide

Introduction

The protein encoded by this gene is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimers disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. This protein also exhibits an bactericidal, antimicrobial activity.

Alternative Names

IAPP; Islet amyloid polypeptide; DAP; IAP; amylin

Gene ID

3375

UniProt

P10997

Subcellular Location

Secreted

Cell Line Specificity

Cancer enhanced

Function

Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes (By similarity). Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs (By similarity).

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