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Anti-Hypusine Monoclonal Antibody (10G3)
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Product Description:The Anti-Hypusine antibody is a rabbit monoclonal antibody recommended for use in western blot, ELISA and other applications. This antibody specifically targets Hypusine.Applications:Western Blot, Enzyme-Linked Immunosorbent AssayTarget:HypusineSpecificity:This antibody reacts with Hypusine.Clonality:MonoclonalClone ID:10G3Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEAggregation:<5% as determined by SECForm:LiquidEndotoxin:Please contact us for more information.Formulation:Contact us for custom product formulation.Preservative:BSA and Azide free.Stabilizer:NoneShipping:Shipped at 4°C.Storage:This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-Hypusine Monoclonal Antibody (10G3) Applications
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Note:Optimal dilutions/concentrations should be determined by the end user.
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Introduction
Hypusine is an unusual amino acid found in all eukaryotes and in some archaea, but not in bacteria. The only known protein containing hypusine is eukaryotic translation initiation factor 5A (eIF5A) and a similar protein found in archaebacteria.In humans, two isoforms of eIF-5A have been described: eIF5A-1 and eIF5A-2. They are encoded by two different genes EIF5A and EIF5A2. The protein is involved in protein biosynthesis and promotes the formation of the first peptide bond. The region surrounding the hypusine residue is highly conserved and is essential to the function of eIF5A.Thus, hypusine and eIF-5A appear to be vital for the viability and proliferation of eukaryotic cells.
Alternative Names
Hypusine; Hypusine residue
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