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Anti-HSPB1 Monoclonal Antibody (SAIC-23C-35)
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Product Description:The Anti-HSPB1 antibody is a mouse monoclonal antibody recommended for use in enzyme-linked immunosorbent assay, western blot and other applications. This antibody specifically targets HSPB1 and demonstrates reactivity with human.Applications:Enzyme-Linked Immunosorbent Assay, Western blotTarget:HSPB1Target Species:HumanSpecificity:This antibody reacts with Human HSPB1.Clonality:MonoclonalClone ID:SAIC-23C-35Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEAggregation:<5% as determined by SECConcentration:1 mg/mLForm:LiquidEndotoxin:Please contact us for more information.Formulation:Contact us for custom product formulation.Preservative:BSA and Azide free.Stabilizer:NoneShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-HSPB1 Monoclonal Antibody (SAIC-23C-35) Applications
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Note:Optimal dilutions/concentrations should be determined by the end user.
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Gene Symbol
HSPB1
Protein Name
Heat shock protein beta-1
Introduction
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis.
Alternative Names
CMT2F; HMN2B; HMND3; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102
Gene ID
UniProt
Subcellular Location
Cytoplasm
Tissue Specificity
Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle.
Cell Line Specificity
Low cancer specificity
Function
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state.
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