Anti-HRV14 NIm-IA Monoclonal Antibody (17-IA)

Anti-HRV14 NIm-IA Monoclonal Antibody (17-IA)

Cat No: ASPC637

Summary
Host Species:
Mouse
Species Reactivity:
Human Rhinovirus 14
Applications:
Enzyme-Linked Immunosorbent Assay, Neutralization
Clone ID:
17-IA
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC637 Anti-HRV14 NIm-IA Antibody (17-IA) Mouse IgG2a, Kappa None $460 In stock
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ASPC637-P Anti-HRV14 NIm-IA Antibody (17-IA), PE Mouse IgG2a, Kappa PE $1,180 2-3 weeks
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ASPC637-A Anti-HRV14 NIm-IA Antibody (17-IA), APC Mouse IgG2a, Kappa APC $980 2-3 weeks
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ASPC637-H Anti-HRV14 NIm-IA Antibody (17-IA), HRP Mouse IgG2a, Kappa HRP $600 2-3 weeks
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ASPC637-B Anti-HRV14 NIm-IA Antibody (17-IA), Biotin Mouse IgG2a, Kappa Biotin $680 2-3 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-HRV14 NIm-IA Monoclonal Antibody (17-IA)
    • Product Description:
      The Anti-HRV14 NIm-IA antibody is a mouse monoclonal antibody recommended for use in ELISA, neutralization and other applications. This antibody specifically targets HRV14 NIm-IA.
      Applications:
      Enzyme-Linked Immunosorbent Assay, Neutralization
      Target:
      HRV14 NIm-IA
      Target Species:
      Human Rhinovirus 14
      Specificity:
      This antibody reacts with HRV14.
      Clonality:
      Monoclonal
      Clone ID:
      17-IA
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-HRV14 NIm-IA Monoclonal Antibody (17-IA) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Introduction
The human rhinovirus 14 (HRV14) capsid exhibits a pseudo-T=3 (P=3) icosahedral symmetry and consists of 60 copies each of four viral proteins, VP1, VP2, VP3, and VP4, with VP4 at the RNA-capsid interface. An ∼20-Å deep canyon lies roughly at the junction of VP1 (forming the north rim) with VP2 and VP3 (forming the south rim) and surrounds each of the 12 icosahedral fivefold vertices. The canyon regions of HRV14 and HRV16, both major receptor group rhinoviruses, were shown to contain the binding site of the cellular receptor, intercellular adhesion molecule 1 (ICAM-1). Four major neutralizing immunogenic (NIm) sites, NIm-IA, NIm-IB, NIm-II, and NIm-III, were identified by studies of neutralization escape mutants with monoclonal antibodies (MAbs) and then mapped to four protruding regions on the viral surface.
Alternative Names
Human Rhinovirus 14; HRV14; VP1
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