Anti-HMGA2 Monoclonal Antibody (B-5H1)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C934	Anti-HMGA2 Antibody (B-5H1)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C934

Anti-HMGA2 Antibody (B-5H1)

Mouse IgG

None

$460

Add

Anti-HMGA2 Monoclonal Antibody (B-5H1)
- Product Description:
  
  The Anti-HMGA2 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human HMGA2.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  HMGA2
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human High Mobility Group AT-Hook 2 (HMGA2).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  B-5H1
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-HMGA2 Monoclonal Antibody (B-5H1) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

High mobility group protein HMGI-C

Introduction

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative Names

BABL; HMGI-C; HMGIC; LIPO; STQTL9

Gene ID

8091

UniProt

P52926

Related Disease

Silver-Russell syndrome 5 (SRS5)

Subcellular Location

Nucleus.

Cell Line Specificity

Low cancer specificity