Anti-HIV-1 gp41 Monoclonal Antibody (A7)

Subcat	Description	Isotype	Conjugate	Price
ASPC1163	Anti-HIV-1 gp41 Antibody (A7)	Human IgG1, Lambda	None	$460	Add
ASPC1163-A	Anti-HIV-1 gp41 Antibody (A7), APC	Human IgG1, Lambda	APC	$980	Add
ASPC1163-B	Anti-HIV-1 gp41 Antibody (A7), Biotin	Human IgG1, Lambda	Biotin	$680	Add
ASPC1163-H	Anti-HIV-1 gp41 Antibody (A7), HRP	Human IgG1, Lambda	HRP	$600	Add
ASPC1163-P	Anti-HIV-1 gp41 Antibody (A7), PE	Human IgG1, Lambda	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1163

Anti-HIV-1 gp41 Antibody (A7)

Human IgG1, Lambda

None

$460

Add

ASPC1163-A

Anti-HIV-1 gp41 Antibody (A7), APC

Human IgG1, Lambda

APC

$980

Add

ASPC1163-B

Anti-HIV-1 gp41 Antibody (A7), Biotin

Human IgG1, Lambda

Biotin

$680

Add

ASPC1163-H

Anti-HIV-1 gp41 Antibody (A7), HRP

Human IgG1, Lambda

HRP

$600

Add

ASPC1163-P

Anti-HIV-1 gp41 Antibody (A7), PE

Human IgG1, Lambda

$1,180

Add

Anti-HIV-1 gp41 Monoclonal Antibody (A7)
- Product Description:
  
  The Anti-HIV-1 gp41 antibody is a human monoclonal antibody recommended for use in enzyme-linked immunosorbent assay, functional assay, neutralization and other applications. This antibody specifically targets HIV-1 gp41.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Functional Assay, Neutralization
  
  Source:
  
  Human
  
  Target:
  
  HIV-1 gp41
  
  Specificity:
  
  This antibody reacts with HIV-1 gp41.
  
  Immunogen:
  
  Recombinant gp140 envelope protein.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  A7
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-HIV-1 gp41 Monoclonal Antibody (A7) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Introduction

The Env gene codes for the gp160 protein which forms a homotrimer, and is cleaved into gp120 and gp41 by the host cell protease, Furin. To form an active fusion protein, gp120 and gp41 polypeptides remain non-covalently bound together, but this interaction is often not stable, leading to shed, soluble gp120 and membrane-bound, gp41 'stumps'. Separately, cleavage by furin is inefficient, and virions often are released with inactive, uncleaved gp160. Because of the high prevalence of these inactive forms, the immune system often produces antibodies which target inactive Env, rather than active forms of the envelope protein.

Alternative Names

HIV-1; Human immunodeficiency virus; HIV-1 gp41

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