Anti-HIV-1 gp160 Monoclonal Antibody (2A6)

Anti-HIV-1 gp160 Monoclonal Antibody (2A6)

Cat No: ASPC260

Summary
Host Species:
Human
Species Reactivity:
Human Immunodeficiency Virus Type 1
Applications:
Neutralization
Clone ID:
2A6
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC260 Anti-HIV-1 gp160 Antibody (2A6) Human IgG1, Kappa None $460 4-6 weeks
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ASPC260-P Anti-HIV-1 gp160 Antibody (2A6), PE Human IgG1, Kappa PE $1,180 4-6 weeks
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ASPC260-A Anti-HIV-1 gp160 Antibody (2A6), APC Human IgG1, Kappa APC $980 4-6 weeks
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ASPC260-H Anti-HIV-1 gp160 Antibody (2A6), HRP Human IgG1, Kappa HRP $600 4-6 weeks
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ASPC260-B Anti-HIV-1 gp160 Antibody (2A6), Biotin Human IgG1, Kappa Biotin $680 4-6 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-HIV-1 gp160 Monoclonal Antibody (2A6)
    • Product Description:
      The Anti-HIV-1 gp160 antibody is a human monoclonal antibody recommended for use in neutralization and other applications. This antibody specifically targets HIV-1 gp160.
      Applications:
      Neutralization
      Target:
      HIV-1 gp160
      Target Species:
      Human Immunodeficiency Virus Type 1
      Specificity:
      This antibody reacts with HIV-1 gp160.
      Clonality:
      Monoclonal
      Clone ID:
      2A6
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-HIV-1 gp160 Monoclonal Antibody (2A6) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
env
Protein Name
Envelope glycoprotein gp160
Introduction
The Env gene codes for the gp160 protein which forms a homotrimer, and is cleaved into gp120 and gp41 by the host cell protease, Furin. To form an active fusion protein, gp120 and gp41 polypeptides remain non-covalently bound together, but this interaction is often not stable, leading to shed, soluble gp120 and membrane-bound, gp41 'stumps'. Separately, cleavage by furin is inefficient, and virions often are released with inactive, uncleaved gp160. Because of the high prevalence of these inactive forms, the immune system often produces antibodies which target inactive Env, rather than active forms of the envelope protein.
Alternative Names
ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain
Gene ID
UniProt
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