Anti-HDAC4 Monoclonal Antibody (G-6C7)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C911	Anti-HDAC4 Antibody (G-6C7)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C911

Anti-HDAC4 Antibody (G-6C7)

Mouse IgG

None

$460

Add

Anti-HDAC4 Monoclonal Antibody (G-6C7)
- Product Description:
  
  The Anti-HDAC4 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human HDAC4.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  HDAC4
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Histone Deacetylase 4 (HDAC4).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  G-6C7
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-HDAC4 Monoclonal Antibody (G-6C7) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Histone deacetylase 4

Introduction

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Alternative Names

AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA

Gene ID

9759

UniProt

P56524

Subcellular Location

Nucleus. Cytoplasm.

Tissue Specificity

Ubiquitous.

Cell Line Specificity

Low cancer specificity