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Anti-HAVCR1 Monoclonal Antibody (11A10)
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Product Description:The Anti-HAVCR1 antibody is a mouse monoclonal antibody recommended for use in flow cytometry, Immunoblotting, inhibition, functional assay, ELISA, immunoprecipitation, immunofluorescence and other applications. This antibody specifically targets HAVCR1 and demonstrates reactivity with human.Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunoblotting, Inhibition, Functional Assay, Western Blot, Immunoprecipitation, ImmunofluorescenceTarget:HAVCR1Target Species:HumanSpecificity:This antibody reacts with human HAVCR1.Immunogen:Human HAVCR1 proteinClonality:MonoclonalClone ID:11A10Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEAggregation:<5% as determined by SECForm:LiquidEndotoxin:Please contact us for more information.Formulation:Contact us for custom product formulation.Preservative:BSA and Azide free.Stabilizer:NoneShipping:Shipped at 4°C.Storage:This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-HAVCR1 Monoclonal Antibody (11A10) Applications
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Note:Optimal dilutions/concentrations should be determined by the end user.
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Gene Symbol
HAVCR1
Protein Name
Hepatitis A virus cellular receptor 1
Introduction
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene.
Alternative Names
HAVCR1; hepatitis A virus cellular receptor 1; TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1; kidney injury molecule 1; T-cell membrane protein 1; T-cell immunoglobulin mucin receptor 1; T-cell immunoglobulin mucin family member 1; T cell immunoglobin domain and mucin domain protein 1; ARD5
Gene ID
UniProt
Molecule Mass
CD Molecules
Subcellular Location
Cell membrane
Tissue Specificity
Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.
Cell Line Specificity
Cancer enriched
Function
Phosphatidylserine receptor that plays an important functional role in regulatory B-cells homeostasis including generation, expansion and suppressor functions (By similarity).
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