Anti-HAMP Monoclonal Antibody (1A3)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC362	Anti-HAMP Antibody (1A3)	Human IgG1	None	$460	In stock	Add
ASPC362-P	Anti-HAMP Antibody (1A3), PE	Human IgG1	PE	$1,180	2-3 weeks	Add
ASPC362-A	Anti-HAMP Antibody (1A3), APC	Human IgG1	APC	$980	2-3 weeks	Add
ASPC362-H	Anti-HAMP Antibody (1A3), HRP	Human IgG1	HRP	$600	2-3 weeks	Add
ASPC362-B	Anti-HAMP Antibody (1A3), Biotin	Human IgG1	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC362

Anti-HAMP Antibody (1A3)

Human IgG1

None

$460

In stock

Add

ASPC362-P

Anti-HAMP Antibody (1A3), PE

Human IgG1

$1,180

2-3 weeks

Add

ASPC362-A

Anti-HAMP Antibody (1A3), APC

Human IgG1

APC

$980

2-3 weeks

Add

ASPC362-H

Anti-HAMP Antibody (1A3), HRP

Human IgG1

HRP

$600

2-3 weeks

Add

ASPC362-B

Anti-HAMP Antibody (1A3), Biotin

Human IgG1

Biotin

$680

2-3 weeks

Add

Anti-HAMP Monoclonal Antibody (1A3)
- Product Description:
  
  The Anti-HAMP antibody is a human monoclonal antibody recommended for use in ELISA, inhibition, flow cytometry and other applications. This antibody specifically targets HAMP and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Inhibition, Flow Cytometry
  
  Target:
  
  Hepcidin
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Hepcidin.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  1A3
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-HAMP Monoclonal Antibody (1A3) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

HAMP

Protein Name

Hepcidin

Introduction

The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.

Alternative Names

HAMP; hepcidin antimicrobial peptide; HEPC; PLTR; HFE2B; LEAP1

Gene ID

57817

UniProt

P81172

Related Disease

Hemochromatosis 2B (HFE2B)

Subcellular Location

Secreted

Cell Line Specificity

Cancer enriched

Function

Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues.

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