Anti-GRK2 Monoclonal Antibody (B-6D7)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C875	Anti-GRK2 Antibody (B-6D7)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C875

Anti-GRK2 Antibody (B-6D7)

Mouse IgG

None

$460

Add

Anti-GRK2 Monoclonal Antibody (B-6D7)
- Product Description:
  
  The Anti-GRK2 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human GRK2.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  GRK2
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human G Protein-Coupled Receptor Kinase 2 (GRK2).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  B-6D7
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-GRK2 Monoclonal Antibody (B-6D7) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Beta-adrenergic receptor kinase 1

Introduction

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.

Alternative Names

ADRBK1; BARK1; BETA-ARK1

Gene ID

156

UniProt

P25098

Subcellular Location

Cytoplasm

Tissue Specificity

Expressed in peripheral blood leukocytes.

Cell Line Specificity

Low cancer specificity