Anti-GPR37 Monoclonal Antibody (C-12F2)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C861	Anti-GPR37 Antibody (C-12F2)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C861

Anti-GPR37 Antibody (C-12F2)

Mouse IgG

None

$460

Add

Anti-GPR37 Monoclonal Antibody (C-12F2)
- Product Description:
  
  The Anti-GPR37 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human GPR37.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  GPR37
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human G Protein-Coupled Receptor 37 (GPR37).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  C-12F2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-GPR37 Monoclonal Antibody (C-12F2) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Prosaposin receptor GPR37

Introduction

This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease.

Alternative Names

EDNRBL; PAELR; hET(B)R-LP

Gene ID

2861

UniProt

O15354

Subcellular Location

Cell projection, dendrite

Tissue Specificity

Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).

Cell Line Specificity

Cancer enhanced

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