Anti-GP Monoclonal Antibody - Amerigo Scientific

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price
ASPC099	Anti-GP Antibody	Human IgG1, Kappa		None	$460	Add
ASPC099-P	Anti-GP Antibody, PE	Human IgG1, Kappa		PE	$1,180	Add
ASPC099-A	Anti-GP Antibody, APC	Human IgG1, Kappa		APC	$980	Add
ASPC099-H	Anti-GP Antibody, HRP	Human IgG1, Kappa		HRP	$600	Add
ASPC099-B	Anti-GP Antibody, Biotin	Human IgG1, Kappa		Biotin	$680	Add
ASPC099-4	Anti-GP Antibody, Fc Silenced	Human IgG1, Kappa	Fc Silenced	None	$980	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC099

Anti-GP Antibody

Human IgG1, Kappa

None

$460

Add

ASPC099-P

Anti-GP Antibody, PE

Human IgG1, Kappa

$1,180

Add

ASPC099-A

Anti-GP Antibody, APC

Human IgG1, Kappa

APC

$980

Add

ASPC099-H

Anti-GP Antibody, HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC099-B

Anti-GP Antibody, Biotin

Human IgG1, Kappa

Biotin

$680

Add

ASPC099-4

Anti-GP Antibody, Fc Silenced

Human IgG1, Kappa

Fc Silenced

None

$980

Add

Anti-GP Monoclonal Antibody
- Product Description:
  
  The antibody targets an epitope on the GP1 subunit that is conserved across different members of the filovirus family, which includes viruses like Ebola virus (EBOV) and Marburg virus (MARV).
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Neutralization
  
  Source:
  
  Human
  
  Target:
  
  GP
  
  Specificity:
  
  GP1 epitope
  
  Clonality:
  
  Monoclonal
  
  Isotype:
  
  Human IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-GP Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

Protein Name

Envelope glycoprotein

Introduction

GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection).

Alternative Names

MARV; Marburg virus (strain Kenya/Ravn/1987)); GP; Envelope glycoprotein; GP1

UniProt

P35253

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