Anti-GP Monoclonal Antibody (7B5)

Anti-GP Monoclonal Antibody (7B5)

Cat No: ASPC541

Summary
Host Species:
Mouse
Species Reactivity:
Marburg Virus
Applications:
Enzyme-Linked Immunosorbent Assay, Western Blot, Immunoprecipitation
Clone ID:
7B5
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC541 Anti-GP Antibody (7B5) Mouse IgG1, Kappa None $460 In stock
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ASPC541-P Anti-GP Antibody (7B5), PE Mouse IgG1, Kappa PE $1,180 2-3 weeks
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ASPC541-A Anti-GP Antibody (7B5), APC Mouse IgG1, Kappa APC $980 2-3 weeks
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ASPC541-H Anti-GP Antibody (7B5), HRP Mouse IgG1, Kappa HRP $600 2-3 weeks
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ASPC541-B Anti-GP Antibody (7B5), Biotin Mouse IgG1, Kappa Biotin $680 2-3 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-GP Monoclonal Antibody (7B5)
    • Product Description:
      The Anti-GP antibody is a mouse monoclonal antibody recommended for use in western blot, immunoprecipitation and other applications. This antibody specifically targets GP.
      Applications:
      Enzyme-Linked Immunosorbent Assay, Western Blot, Immunoprecipitation
      Target:
      GP
      Target Species:
      Marburg Virus
      Specificity:
      This antibody reacts with GP.
      Clonality:
      Monoclonal
      Clone ID:
      7B5
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-GP Monoclonal Antibody (7B5) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
GP
Protein Name
Envelope glycoprotein
Introduction
Marburg virus is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus. Marburg virus (MARV) causes Marburg virus disease in humans and nonhuman primates, a form of viral hemorrhagic fever. The virus is considered to be extremely dangerous. The WHO rates it as a Risk Group 4 Pathogen (requiring biosafety level 4-equivalent containment).
Alternative Names
GP; Envelope glycoprotein; MARV GP; Marburg virus
Gene ID
UniProt
Function
GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection) (By similarity).
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