Anti-GNLY Monoclonal Antibody (F-6B5)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C846	Anti-GNLY Antibody (F-6B5)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C846

Anti-GNLY Antibody (F-6B5)

Mouse IgG

None

$460

Add

Anti-GNLY Monoclonal Antibody (F-6B5)
- Product Description:
  
  The Anti-GNLY antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human GNLY.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  GNLY
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Granulysin (GNLY).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  F-6B5
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-GNLY Monoclonal Antibody (F-6B5) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Granulysin

Introduction

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative Names

D2S69E; LAG-2; LAG2; NKG5; TLA519

Gene ID

10578

UniProt

P22749

Subcellular Location

Secreted.

Tissue Specificity

Expressed in natural killer and T-cells.

Cell Line Specificity

Group enriched

Function

Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.

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