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Anti-GNA11 Monoclonal Antibody (F-7C7)
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Product Description:The Anti-GNA11 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human GNA11.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:GNA11Target Species:HumanSpecificity:This antibody reacts with human G Protein Subunit Alpha 11 (GNA11).Clonality:MonoclonalClone ID:F-7C7Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-GNA11 Monoclonal Antibody (F-7C7) Applications
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Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
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Protein Name
Guanine nucleotide-binding protein subunit alpha-11
Introduction
The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.
Alternative Names
FBH; FBH2; FHH2; GNA-11; HHC2; HYPOC2
Gene ID
UniProt
Related Disease
Hypocalciuric hypercalcemia, familial 2 (HHC2)
Subcellular Location
Cell membrane
Tissue Specificity
Expressed in testis.
Cell Line Specificity
Low cancer specificity
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