Anti-GDF6 Monoclonal Antibody (G-3G4)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C814	Anti-GDF6 Antibody (G-3G4)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C814

Anti-GDF6 Antibody (G-3G4)

Mouse IgG

None

$460

Add

Anti-GDF6 Monoclonal Antibody (G-3G4)
- Product Description:
  
  The Anti-GDF6 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human GDF6.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  GDF6
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Growth Differentiation Factor 6 (GDF6).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  G-3G4
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-GDF6 Monoclonal Antibody (G-3G4) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Growth/differentiation factor 6

Introduction

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis.

Alternative Names

BMP-13; BMP13; CDMP2; KFM; KFS; KFS1; KFSL; SGM1

Gene ID

392255

UniProt

Q6KF10

Related Disease

Klippel-Feil syndrome 1, autosomal dominant (KFS1)

Subcellular Location

Secreted

Cell Line Specificity

Group enriched