Anti-GCLM Monoclonal Antibody (H-8A9)

Anti-GCLM Monoclonal Antibody (H-8A9)

Cat No: ASZ1C808

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
Clone ID:
H-8A9
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASZ1C808 Anti-GCLM Antibody (H-8A9) Mouse IgG None $460
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  • Anti-GCLM Monoclonal Antibody (H-8A9)
    • Product Description:
      The Anti-GCLM antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human GCLM.
      Applications:
      Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
      Source:
      Mouse
      Target:
      GCLM
      Target Species:
      Human
      Specificity:
      This antibody reacts with human Glutamate-Cysteine Ligase Modifier Subunit (GCLM).
      Clonality:
      Monoclonal
      Clone ID:
      H-8A9
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      0.02% sodium azide
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-GCLM Monoclonal Antibody (H-8A9) Applications
    • Recommended Dilution:
      Western Blot: 1:500-1:5000
      Immunohistochemistry: 1:50-1:200
      Immunocytochemistry: 1:50-1:200
      Note:
      Optimal dilutions/concentrations should be determined by the end user.
Protein Name
Glutamate--cysteine ligase regulatory subunit
Introduction
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Names
GLCLR
Gene ID
UniProt
Tissue Specificity
In all tissues examined. Highest levels in skeletal muscle.
Cell Line Specificity
Cancer enriched
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